- Challenge to Florida program that allowed students at failing schools to receive a voucher permitting them to attend not only neighboring public schools but also private schools, including religious schools.
- Challenge to "Philosophy of Design" class taught at public high school in California that advocated young-earth creationism and intelligent design.
In March 2013, Robert Ingersoll sought to buy flower arrangements for his wedding from his favorite florist, Arlene’s Flowers, which is a for-profit florist shop. The store’s owner informed him that she would not serve him on this occasion, because she believed Ingersoll’s marriage to a man was a sin.
- Discrimination challenge under the Fair Housing Act by a woman who was terminated from a faith-based rehabilitation program because she failed to demonstrate adequate interest in adopting the Christian faith.
- Challenge to the expansion of a Milwaukee voucher program to include parochial and sectarian schools.
Two same-sex couples challenged the Arkansas marriage laws that limited marriage to between a man and a woman. In November 2014, the trial court struck down these laws as an unconstitutional violation of same-sex couples’ fundamental right to marry.
A California public high-school teacher displayed large banners in his classroom with the following text: "IN GOD WE TRUST," "ONE NATION UNDER GOD," "GOD BLESS AMERICA," "GOD SHED HIS GRACE ON THEE," and "All Men Are Created Equal They Are Endowed By Their CREATOR." After the teacher refused to provide those with greater historical context so as to avoid promoting religion, the school district instructed the teach
For years, the Forsyth County Board of Supervisors invited local clergy to deliver sectarian prayers at Board meetings; most of the prayers were Christian. In March 2007, the plaintiffs Americans United and the ACLU of North Carolina challenged the Board’s prayer policy in federal court.
- Challenge to California law exempting religiously-affiliated institutions from adhering to the state's anti-discrimination laws even when the discrimination is not based on religion.
- Challenge to seal used by the Superior Court of Richmond County, Georgia, which contains a reference to the Ten Commandments.